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KMID : 0356920150680020101
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Korean Journal of Anesthesiology
2015 Volume.68 No. 2 p.101 ~ p.105
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Transfusion-related acute lung injury; clinical perspectives
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Kim Jeong-Min
Na Sung-Won
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Abstract
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Transfusion-related acute lung injury (TRALI) was introduced in 1983 to describe a clinical syndrome seen within 6 h of a plasma-containing blood products transfusion. TRALI is a rare transfusion complication; however, the FDA has suggested that TRALI is the leading cause of transfusion-related mortality. Understanding the pathogenesis of TRALI will facilitate adopting preventive strategies, such as deferring high plasma volume female product donors. This review outlines the clinical features, pathogenesis, treatment, and prevention of TRALI.
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KEYWORD
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Acute lung injury, Diagnosis, Etiology, Prevention and control, Prognosis, Transfusion reaction
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